Pub. Date : 1998 Apr
PMID : 9839700
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bradykinin (BK) and thrombin are known to cause a significant time- and concentration-dependent burst of prostanoid biosynthesis in cultured human periodontal-ligament (PDL) cells. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |
| 2 | The aim now was to investigate interactive effects between interleukin 1 alpha, -beta (IL-1 alpha, -1 beta), tumour necrosis factor-alpha,-beta (TNF-alpha, -beta) and BK or thrombin on prostaglandin biosynthesis in human PDL cells. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |
| 3 | Synergistic stimulation of prostanoid biosynthesis was demonstrated when BK or thrombin were added together with <protein-id="3552">IL-1 alpha or -1 beta. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |
| 4 | These experiments demonstrate synergistic interactions between BK, thrombin, IL-1 and TNF on prostaglandin biosynthesis in cultured human PDL cells. | Prostaglandins | coagulation factor II, thrombin | Homo sapiens |