Title : Microinjections of dopamine agonists and cocaine elevate plasma corticosterone: dissociation effects among the ventral and dorsal striatum and medial prefrontal cortex.

Pub. Date : 1998 Dec 14

PMID : 9838097






3 Functional Relationships(s)
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1 The highest dose tested (18 nmol) of a mixture of the dopamine D1 receptor agonist SKF 38393 and the D2 agonist quinpirole (SKF/Quin) increased plasma CORT when injected into each of the three brain regions. 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide cortistatin Rattus norvegicus
2 Microinjections of the medium dose (i.e., 3 nmol) of SKF/Quin into the VStr also increased plasma CORT, while the injections into the MPC and DStr did not. 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide cortistatin Rattus norvegicus
3 Systemic pretreatment with haloperidol attenuated the elevated CORT induced by intra-VStr injections of SKF/Quin. 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide cortistatin Rattus norvegicus