Title : Correction of the PNH defect by GPI-anchored protein transfer.

Pub. Date : 1998 Dec 1

PMID : 9834251






1 Functional Relationships(s)
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1 Pretreatment of microvesicles, RBC eluate preparations, and HDL with phosphatidylinositol-specific, phospholipase C, abrogated protein transfer to deficient cells, indicating that increased cell-associated CD55 and CD59 levels were related to insertion of the intact GPI moiety, rather than to simple adhesion. Phosphatidylinositols CD59 molecule (CD59 blood group) Homo sapiens