Title : Ca2+ regulation of gelsolin activity: binding and severing of F-actin.

Pub. Date : 1998 Dec

PMID : 9826630






2 Functional Relationships(s)
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1 The data suggest that binding of Ca2+ to the gelsolin-F-actin complex is the rate-limiting step for F-actin severing by gelsolin; this Ca2+ binding event is a committed step that results in a Ca2+ ion bound at a high-affinity, EGTA-resistant site. Egtazic Acid gelsolin Homo sapiens
2 The data suggest that binding of Ca2+ to the gelsolin-F-actin complex is the rate-limiting step for F-actin severing by gelsolin; this Ca2+ binding event is a committed step that results in a Ca2+ ion bound at a high-affinity, EGTA-resistant site. Egtazic Acid gelsolin Homo sapiens