Title : Potent and non-specific inhibition of cytochrome P450 by JM216, a new oral platinum agent.

Pub. Date : 1998 Nov

PMID : 9820175






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Specific substrates of CYP included testosterone (catalysed by CYP3A4), paclitaxel (CYP2C8), 7-ethoxyresorufin (CYP1A1, CYP1A2), coumarin (CYP2A6), aniline (CYP2E1) and (+/-)-bufuralol (CYP2D6). Testosterone cytochrome P450 family 4 subfamily F member 3 Homo sapiens