Title : [Relation between levels of leptin, insulin and cortisol in persons with the 5H (X) syndrome].

Pub. Date : 1998 Feb

PMID : 9820079






2 Functional Relationships(s)
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1 In the elevated leptin level in syndrome 5H (association of hyperinsulinism, hyperglycaemia-NIDDM, hyperlipoproteinaemia with android obesity, arterial hypertension and hirsutism in females with the polycystic ovaries syndrome) participate in a significant way also elevated basal IRI and cortisol levels as well as an elevated postprandial IRI response during oGTT despite the fact that leptin and endothelin-1 levels do not rise significantly during oGTT despite hyperinsulinaemia. Hydrocortisone leptin Homo sapiens
2 Elevated insulin and cortisol levels maintain elevated leptin levels which in turn enhances the insulin resistance in muscles and at the same time has an impact on the IRI response to postprandial hyperglycaemia. Hydrocortisone leptin Homo sapiens