Pub. Date : 1995 Oct
PMID : 9815913
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | To test the hypothesis that a p53 mutation could result in tamoxifen resistance and estrogen-independent growth, the MCF-7 cell line was transfected with p53 cDNA which was mutated at codon 179 (histidine to glutamine). | Tamoxifen | tumor protein p53 | Homo sapiens |
2 | MCF-7 is an estrogen receptor-positive, estrogen-dependent, tamoxifen-sensitive cell line with only wild-type p53. | Tamoxifen | tumor protein p53 | Homo sapiens |