Pub. Date : 1997 Jun
PMID : 9815771
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In IGROV-1/Pt1 cells, cisplatin resistance has been ascribed to a reduced susceptibility to apoptosis as a consequence of p53 mutation and inactivation of its function. | Cisplatin | tumor protein p53 | Homo sapiens |
| 2 | In the A2780 cisplatin-resistant subline, which retained the wild-type p53 gene status, the development of resistance has been possibly related to increased cell ability to repair drug-induced DNA damage. | Cisplatin | tumor protein p53 | Homo sapiens |