Pub. Date : 1998 Sep
PMID : 9807817
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 2 | An Arabidopsis immunophilin, AtFKBP12, binds to AtFIP37 (FKBP interacting protein) in an interaction that is disrupted by FK506. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 3 | The interaction between AtFKBP12 and AtFIP37 in the 2-hybrid system, as assessed by histidine auxotrophy and beta-galactosidase activity, was disrupted by FK506, but not by cyclosporin A, a drug that binds to cyclophilin A. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 4 | The binding was abolished by prior incubation of AtFKBP12 with FK506. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 5 | These findings indicate that an Arabidopsis FKBP12 ortholog encodes a protein that binds FK506 and that the interaction between AtFKBP12 and AtFIP37 may involve the FK506 binding site of AtFKBP12. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 6 | These findings indicate that an Arabidopsis FKBP12 ortholog encodes a protein that binds FK506 and that the interaction between AtFKBP12 and AtFIP37 may involve the FK506 binding site of AtFKBP12. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 7 | These findings indicate that an Arabidopsis FKBP12 ortholog encodes a protein that binds FK506 and that the interaction between AtFKBP12 and AtFIP37 may involve the FK506 binding site of AtFKBP12. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 8 | These findings indicate that an Arabidopsis FKBP12 ortholog encodes a protein that binds FK506 and that the interaction between AtFKBP12 and AtFIP37 may involve the FK506 binding site of AtFKBP12. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 9 | These findings indicate that an Arabidopsis FKBP12 ortholog encodes a protein that binds FK506 and that the interaction between AtFKBP12 and AtFIP37 may involve the FK506 binding site of AtFKBP12. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |
| 10 | These findings indicate that an Arabidopsis FKBP12 ortholog encodes a protein that binds FK506 and that the interaction between AtFKBP12 and AtFIP37 may involve the FK506 binding site of AtFKBP12. | Tacrolimus | FK506-binding protein 12 | Arabidopsis thaliana |