Title : The nature of antioxidant defense mechanisms: a lesson from transgenic studies.

Pub. Date : 1998 Oct

PMID : 9788901






1 Functional Relationships(s)
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1 Transgenic mice overexpressing three isoforms of superoxide dismutase, catalase, and the cellular glutathione peroxidase (GSHPx-1) in various tissues show an increased tolerance to ischemia-reperfusion heart and brain injury, hyperoxia, cold-induced brain edema, adriamycin, and paraquat toxicity. Paraquat catalase Mus musculus