Title : Involvement of DA1 and DA2 receptors in the gastroprotective activity of amylin in the rat.

Pub. Date : 1998 Sep

PMID : 9782073






2 Functional Relationships(s)
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1 Peripheral administration of amylin (40 microg kg-1) exerts gastroprotective effects in the reserpine-induced gastric lesions in the rat. Reserpine islet amyloid polypeptide Rattus norvegicus
2 Our data confirm that the gastroprotective effect of amylin in reserpine-induced gastric lesions involves, at least in part, the dopaminergic transmission, interfering with both the DA1 and DA2 receptor subtypes. Reserpine islet amyloid polypeptide Rattus norvegicus