Title : Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling.

Pub. Date : 1998 Oct 23

PMID : 9774438






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The transamination product of leucine, alpha-ketoisocaproic acid, also stimulates PHAS-I phosphorylation although the transamination products of isoleucine and valine are ineffective. Leucine eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens
2 The branched-chain amino acid, leucine, also exerts similar effects on PHAS-I phosphorylation in isolated pancreatic islets. Leucine eukaryotic translation initiation factor 4E binding protein 1 Homo sapiens