Title : [Double effects of arsenic trioxide (As2O3) on acute promyelocytic leukemic cell line].

Pub. Date : 1997 Jul

PMID : 9772451






4 Functional Relationships(s)
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1 In addition, 0.1-2 mumol/L of As2O3 could rapidly and effectively modulate and degradate PML/PML-RAR alpha proteins. Arsenic Trioxide PML nuclear body scaffold Homo sapiens
2 In addition, 0.1-2 mumol/L of As2O3 could rapidly and effectively modulate and degradate PML/PML-RAR alpha proteins. Arsenic Trioxide PML nuclear body scaffold Homo sapiens
3 CONCLUSION: As2O3 had double effects (induction of apoptosis and imcomplete differentiation) on NB4 cells, which could associate with rapid modulation and degradation of PML/PML-RAR alpha proteins. Arsenic Trioxide PML nuclear body scaffold Homo sapiens
4 CONCLUSION: As2O3 had double effects (induction of apoptosis and imcomplete differentiation) on NB4 cells, which could associate with rapid modulation and degradation of PML/PML-RAR alpha proteins. Arsenic Trioxide PML nuclear body scaffold Homo sapiens