Title : Antisense modulation of the ICAM-1 phenotype of a model human bone marrow stromal cell line.

Pub. Date : 1998 Oct 10

PMID : 9770366






2 Functional Relationships(s)
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1 However, KM-102 ICAM-1 overexpressors demonstrated enhanced binding (2.5-fold) to phorbol ester-treated, but not untreated, LFA-1-bearing JY cells. Phorbol Esters intercellular adhesion molecule 1 Homo sapiens
2 These findings suggest that while ICAM-1 is not required for basal adhesion between stromal and hematopoietic cells, stromal ICAM-1 may contribute to stromal:leukemic cellular interaction when bound to the phorbol ester-dependent high-avidity state of hematopoietic LFA-1. Phorbol Esters intercellular adhesion molecule 1 Homo sapiens