Pub. Date : 1998
PMID : 9764438
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TTX attenuates release of CGRP caused by low concentrations of capsaicin, indicating that an axon reflex mechanism in the peripheral endings of C-fibre afferents can augment local outflow of CGRP. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 2 | TTX attenuates release of CGRP caused by low concentrations of capsaicin, indicating that an axon reflex mechanism in the peripheral endings of C-fibre afferents can augment local outflow of CGRP. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 3 | Outflow of CGRP evoked by low pH and capsaicin have common features, such as sensitivity to RR and CPZ. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 4 | Capsaicin pretreatment resulted in lower myocardial levels of CGRP, and ischaemic myocardium had lower content of CGRP than non-ischaemic areas. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 5 | Capsaicin-treated animals had larger myocardial infarctions, possibly due to depletion of CGRP. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |
| 6 | Based on the present findings it may therefore be suggested that local cardiac CGRP-release from capsaicin-sensitive C-fibre afferents during myocardial ischaemia functions as an endogenous physiological protective response. | Capsaicin | calcitonin related polypeptide alpha | Homo sapiens |