Title : Affinity labelling of the estradiol-17 beta dehydrogenase from human placenta with substrate analogs.

Pub. Date : 1976 Sep 15

PMID : 976263






1 Functional Relationships(s)
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1 The alkylation of a histidine residue which is fast and extensive when the alkylation side chain is on the C-3 carbon atom, is dramatically decreased when alkylating side chain is shifted towards rings B and D. These results allow the location of this histidine in the vicinity of ring A and probably on the beta face of the steroid nucleus. Carbon complement C3 Homo sapiens