Title : Cobalamin-dependent methionine synthase and serine hydroxymethyltransferase: targets for chemotherapeutic intervention?

Pub. Date : 1998

PMID : 9762364






1 Functional Relationships(s)
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1 Chemotherapeutic drugs targeted at folate-dependent reactions have typically been directed at a limited number of target enzymes: dihydrofolate reductase, thymidylate synthase, and GAR and AICAR transformylase. Folic Acid dihydrofolate reductase Homo sapiens