Title : Mechanism for inhibition of thyroid peroxidase by leucomalachite green.

Pub. Date : 1998 Sep

PMID : 9760285






1 Functional Relationships(s)
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1 Incubation of LMG with TPO, iodide, and tyrosine in the presence of a H2O2-generating system yielded oxidation products that were identified by using on-line LC/APCI-MS as desmethyl LMG, 2desmethyl LMG, 3desmethyl LMG, MG, and MG N-oxide. Hydrogen Peroxide thyroid peroxidase Homo sapiens