Title : [Inhibition of cytochrome P450 by nitric oxide].

Pub. Date : 1998 Jul

PMID : 9755460






2 Functional Relationships(s)
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1 Although NO reversibly interacts with the heme-iron of P450, the pathophysiological role of this interaction remains to be elucidated. Heme cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 These results suggested that NO might form dissociable complexes with the heme moiety of P450 and irreversibly inactivate them. Heme cytochrome P450 family 2 subfamily B member 6 Homo sapiens