Pub. Date : 1976 Nov
PMID : 975055
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Levels of AHH, the enzyme that metabolizes BaP to its cytotoxic derivatives, were only 2.4 times higher in exponentially growing than in confluent cells, suggesting that cell division was responsible for the large differential toxicity. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 1 | Mus musculus |
| 2 | The results indicate that the metabolism of BaP by AHH to produce cytotoxic metabolites, which may cause lesions that are expressed upon cell division, is responsible for the cytotoxicity of BaP to NMuLi. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 1 | Mus musculus |
| 3 | The results indicate that the metabolism of BaP by AHH to produce cytotoxic metabolites, which may cause lesions that are expressed upon cell division, is responsible for the cytotoxicity of BaP to NMuLi. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 1 | Mus musculus |