Title : Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells.

Pub. Date : 1998 Sep 15

PMID : 9743343






1 Functional Relationships(s)
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1 TRAIL-induced death was characterized by caspase activation and cellular protein cleavage within minutes of TRAIL addition, and death could be completely inhibited by the caspase inhibitors Ile-Glu-Thr-Asp (IETD) and Val-Ala-Asp (VAD), indicating the presence of a TRAIL receptor signaling pathway similar to that identified for Fas and TNF receptors. VAD I protocol TNF superfamily member 10 Homo sapiens