Title : Functional properties of a naturally occurring isoform of soluble guanylyl cyclase.

Pub. Date : 1998 Oct 1

PMID : 9742221






1 Functional Relationships(s)
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1 The new NO-independent activator, 3-(5"-hydroxymethyl-2"-furyl)-1-benzyl indazole (YC-1), increased the maximal NO-stimulated activity of the new isoform, caused a leftward-shift in the NO concentration-response curve and turned CO into an effective activator, as it did for the alpha1 beta1 heterodimer (200-fold activation). 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens