Title : Effect of selective inhibition of the inducible cyclooxygenase on renin release in healthy volunteers.

Pub. Date : 1998 Aug

PMID : 9737091






3 Functional Relationships(s)
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1 Therefore, we assessed the effects of meloxicam, a selective inhibitor of COX-2, and indomethacin, an unselective inhibitor of COX-1 and COX-2, on furosemide stimulated plasma renin activity (PRA). Furosemide renin Homo sapiens
2 CONCLUSION: Meloxicam inhibited furosemide stimulated renin release, suggesting that in man COX-2 is responsible for prostaglandin synthesis mediating renin release. Furosemide renin Homo sapiens
3 CONCLUSION: Meloxicam inhibited furosemide stimulated renin release, suggesting that in man COX-2 is responsible for prostaglandin synthesis mediating renin release. Furosemide renin Homo sapiens