Pub. Date : 1998 Oct 1
PMID : 9736460
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Opposing effects of cyclosporin A and tyrphostin AG-1478 indicate a role for Src protein in the cellular control of mineralization. | Cyclosporine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 2 | Under CsA, Src protein quantity decreased on day 8, but its cleavage product (52/54 kDa) was sixfold more abundant then on day 7. | Cyclosporine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 3 | The results indicate that increased Src protein cleavage product on day 8 by CsA is associated with mineralization inhibition, which is opposed by DMSO and 50-microM AG-1478, thus antagonizing the effect of CsA on mineralization. | Cyclosporine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 4 | The results indicate that increased Src protein cleavage product on day 8 by CsA is associated with mineralization inhibition, which is opposed by DMSO and 50-microM AG-1478, thus antagonizing the effect of CsA on mineralization. | Cyclosporine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
| 5 | Direct or indirect interaction between Src and TPP, antagonistically affected by CsA and AG-1478, is likely to underlay cellular control of mineralization. | Cyclosporine | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |