Pub. Date : 1998 Oct
PMID : 9731749
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of glucose transport by angiotensin II and glucose in cultured vascular smooth muscle cells. | Glucose | angiotensinogen | Homo sapiens |
| 2 | Glucose transport in response to angiotensin II (AII) was assessed in cultured vascular smooth muscle (VSM) cells by measuring the uptake of [3H]-2-deoxyglucose, a radiolabeled non-metabolizable glucose analog. | Glucose | angiotensinogen | Homo sapiens |
| 3 | Glucose transport in response to angiotensin II (AII) was assessed in cultured vascular smooth muscle (VSM) cells by measuring the uptake of [3H]-2-deoxyglucose, a radiolabeled non-metabolizable glucose analog. | Glucose | angiotensinogen | Homo sapiens |
| 4 | AII-stimulated transport was also blocked when cells were incubated with cycloheximide for 6 hr, suggesting that protein synthesis is required for the long-term effects of AII on glucose transport. | Glucose | angiotensinogen | Homo sapiens |
| 5 | AII-stimulated transport was also blocked when cells were incubated with cycloheximide for 6 hr, suggesting that protein synthesis is required for the long-term effects of AII on glucose transport. | Glucose | angiotensinogen | Homo sapiens |
| 6 | Inhibition of protein kinase C (PKC) by bisindolylmaleimide and staurosporine did not affect VSM responsiveness to AII, suggesting that AII is capable of stimulating glucose transport through a PKC-independent mechanism; however, VSM responsiveness to AII did appear to be dependent upon the presence of extracellular calcium. | Glucose | angiotensinogen | Homo sapiens |
| 7 | Inhibition of protein kinase C (PKC) by bisindolylmaleimide and staurosporine did not affect VSM responsiveness to AII, suggesting that AII is capable of stimulating glucose transport through a PKC-independent mechanism; however, VSM responsiveness to AII did appear to be dependent upon the presence of extracellular calcium. | Glucose | angiotensinogen | Homo sapiens |
| 8 | The importance of calmodulin in mediating the response of VSM cells to AII was indicated by the inhibition of AII-stimulated glucose transport when VSM cells were incubated in the presence of the calmodulin inhibitors, calmidazolium and W7. | Glucose | angiotensinogen | Homo sapiens |
| 9 | The importance of calmodulin in mediating the response of VSM cells to AII was indicated by the inhibition of AII-stimulated glucose transport when VSM cells were incubated in the presence of the calmodulin inhibitors, calmidazolium and W7. | Glucose | angiotensinogen | Homo sapiens |
| 10 | This was accompanied by a corresponding decrease in the relative effectiveness of AII in stimulating glucose uptake. | Glucose | angiotensinogen | Homo sapiens |