Title : Dopamine formation from tyramine by CYP2D6.

Pub. Date : 1998 Aug 28

PMID : 9731223






2 Functional Relationships(s)
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1 Among the 11 isoforms of human CYP expressed in yeast, CYP2D6 was the only isoform exhibiting strong ability to convert p-tyramine and m-tyramine to dopamine. 3-tyramine cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 The Km values of CYP2D6, expressed in yeast, for p-tyramine and m-tyramine were 190.1 +/- 19.5 microM and 58.2 +/- 13.8 microM, respectively. 3-tyramine cytochrome P450 family 2 subfamily D member 6 Homo sapiens