Title : Dopamine formation from tyramine by CYP2D6.

Pub. Date : 1998 Aug 28

PMID : 9731223






3 Functional Relationships(s)
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1 In this study, we investigated the formation of dopamine from trace amines, using human hepatic microsomes and human cytochrome P450 (CYP) isoforms expressed in yeast. Dopamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 In this study, we investigated the formation of dopamine from trace amines, using human hepatic microsomes and human cytochrome P450 (CYP) isoforms expressed in yeast. Dopamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens
3 Among the 11 isoforms of human CYP expressed in yeast, CYP2D6 was the only isoform exhibiting strong ability to convert p-tyramine and m-tyramine to dopamine. Dopamine cytochrome P450 family 4 subfamily F member 3 Homo sapiens