Title : Possible rare involvement of O6-methylguanine formation as a significant mutational factor in mouse urinary bladder carcinogenesis models.

Pub. Date : 1998

PMID : 9728794






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 O6-methylguanine-DNA methyltransferase (MGMT), which repairs methylated guanine bases, might prevent the G:C to A:T transition, and transgenic mice carrying this MGMT gene have been reported to be less sensitive to the carcinogenicity of certain alkylating agents. Guanine O-6-methylguanine-DNA methyltransferase Mus musculus
2 O6-methylguanine-DNA methyltransferase (MGMT), which repairs methylated guanine bases, might prevent the G:C to A:T transition, and transgenic mice carrying this MGMT gene have been reported to be less sensitive to the carcinogenicity of certain alkylating agents. Guanine O-6-methylguanine-DNA methyltransferase Mus musculus