Pub. Date : 1998 Aug
PMID : 9726815
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phenobarbital treatment increased the number of CYP2A5-positive centrilobular hepatocytes and the CYP2A5-positive areas were extended into the middle zone in all strains, but periportal hepatocytes remained negative. | Phenobarbital | cytochrome P450, family 2, subfamily a, polypeptide 5 | Mus musculus |
| 2 | Phenobarbital treatment increased the number of CYP2A5-positive centrilobular hepatocytes and the CYP2A5-positive areas were extended into the middle zone in all strains, but periportal hepatocytes remained negative. | Phenobarbital | cytochrome P450, family 2, subfamily a, polypeptide 5 | Mus musculus |
| 3 | Fifty percent of the spontaneous foci in untreated mice, over 90% of the foci in mice treated with NDEA or phenobarbital and all of the hepatocellular adenomas and carcinomas displayed positive immunostaining and a strong CYP2A5 mRNA signal by in situ hybridization. | Phenobarbital | cytochrome P450, family 2, subfamily a, polypeptide 5 | Mus musculus |