Pub. Date : 1998 Sep 1
PMID : 9724536
13 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | (1) Where is the GLUT1 ATP binding site? | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 2 | GLUT1 residues 301-364 were identified as one element of the GLUT1 ATP binding domain by peptide mapping and N-terminal sequence analysis of proteolytic fragments of azidoATP-photolabeled GLUT1. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 3 | GLUT1 residues 301-364 were identified as one element of the GLUT1 ATP binding domain by peptide mapping and N-terminal sequence analysis of proteolytic fragments of azidoATP-photolabeled GLUT1. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 4 | GLUT1 residues 301-364 were identified as one element of the GLUT1 ATP binding domain by peptide mapping and N-terminal sequence analysis of proteolytic fragments of azidoATP-photolabeled GLUT1. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 5 | Nucleotide binding and sugar transport experiments undertaken with dimeric and tetrameric forms of GLUT1 indicate that only tetrameric GLUT1 binds and is subject to modulation by ATP. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 6 | Nucleotide binding and sugar transport experiments undertaken with dimeric and tetrameric forms of GLUT1 indicate that only tetrameric GLUT1 binds and is subject to modulation by ATP. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 7 | Reconstitution experiments indicate that nucleotide and tetrameric GLUT1 are sufficient for ATP modulation of sugar transport. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 8 | Feedback control of GLUT1 regulation by ATP was investigated by measuring sugar uptake into erythrocyte ghosts containing or lacking ATP and glycolytic intermediates. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 9 | Feedback control of GLUT1 regulation by ATP was investigated by measuring sugar uptake into erythrocyte ghosts containing or lacking ATP and glycolytic intermediates. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 10 | Reduced cytosolic pH inhibits ATP modulation of GLUT1-mediated 3OMG uptake and increases Kd(app) for ATP interaction with GLUT1. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 11 | Reduced cytosolic pH inhibits ATP modulation of GLUT1-mediated 3OMG uptake and increases Kd(app) for ATP interaction with GLUT1. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 12 | Reduced cytosolic pH inhibits ATP modulation of GLUT1-mediated 3OMG uptake and increases Kd(app) for ATP interaction with GLUT1. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |
| 13 | We conclude that tetrameric but not dimeric GLUT1 is subject to direct regulation by cytosolic ATP and that this regulation is antagonized by intracellular AMP and acidification. | Adenosine Triphosphate | solute carrier family 2 member 1 | Homo sapiens |