Title : The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation.

Pub. Date : 1998 Sep 4

PMID : 9722568






2 Functional Relationships(s)
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1 The in frame deletion of 231 nucleotides of exon 5 resulted in the loss of function of the CaR as measured by calcium-stimulated production of inositol phosphates when transfected into HEK293 cells or keratinocytes. Inositol Phosphates calcium sensing receptor Homo sapiens
2 The full-length CaR was expressed in undifferentiated keratinocytes consistent with their greater response to elevated extracellular calcium in terms of increased intracellular free calcium and production of inositol phosphates. Inositol Phosphates calcium sensing receptor Homo sapiens