Title : Role of NF-kappaB in the antiproliferative effect of endothelin-1 and tumor necrosis factor-alpha in human hepatic stellate cells. Involvement of cyclooxygenase-2.

Pub. Date : 1998 Sep 4

PMID : 9722548






1 Functional Relationships(s)
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1 Induction of COX-2 and stimulation of COX activity by ET-1 and TNF-alpha were prevented by sodium salicylate and MG-132, suggesting that activation of NF-kappaB by either factor is needed for stimulation of COX-2. Sodium Salicylate tumor necrosis factor Homo sapiens