Title : [Relationship between vascular endothelial growth factors and advanced glycation end products in the human vitreous].

Pub. Date : 1998 Jul

PMID : 9720366






3 Functional Relationships(s)
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1 Regarding the relation between VEGF in the vitreous body and pentosidine, an AGE, we compared a diabetic (DM) group (7 eyes) with a nondiabetic (nonDM) group (7 eyes), and investigated the correlation between VEGF and pentosidine by calculating the correlation coefficient. pentosidine vascular endothelial growth factor A Homo sapiens
2 Levels of both VEGF and pentosidine were significantly higher in the DM group (p < 0.01, p < 0.05), and a positive correlation was observed between the levels of VEGF and pentosidine (r = 0.770, p < 0.001). pentosidine vascular endothelial growth factor A Homo sapiens
3 Since it is clear that there is a relation between VEGF and pentosidine in the vitreous body, we speculated that AGE is related to the secretion of cytokine in patients with diabetic retinopathy, and that it affects the development and progression of the disease. pentosidine vascular endothelial growth factor A Homo sapiens