Pub. Date : 1998 Jul
PMID : 9699888
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | HMG-CoA reductase and ACAT inhibitors act synergistically to lower plasma cholesterol and limit atherosclerotic lesion development in the cholesterol-fed rabbit. | Cholesterol | sterol O-acyltransferase 1 | Oryctolagus cuniculus |
2 | HMG-CoA reductase and ACAT inhibitors act synergistically to lower plasma cholesterol and limit atherosclerotic lesion development in the cholesterol-fed rabbit. | Cholesterol | sterol O-acyltransferase 1 | Oryctolagus cuniculus |
3 | We conclude that inhibition of HMG-CoA reductase and ACAT acts synergistically to lower plasma total and lipoprotein cholesterol levels and to limit the development of atherosclerotic lesions in the cholesterol-fed rabbit by presumably regulating cholesterol trafficking pathways within liver and vascular cells. | Cholesterol | sterol O-acyltransferase 1 | Oryctolagus cuniculus |
4 | We conclude that inhibition of HMG-CoA reductase and ACAT acts synergistically to lower plasma total and lipoprotein cholesterol levels and to limit the development of atherosclerotic lesions in the cholesterol-fed rabbit by presumably regulating cholesterol trafficking pathways within liver and vascular cells. | Cholesterol | sterol O-acyltransferase 1 | Oryctolagus cuniculus |