Title : Human buprenorphine N-dealkylation is catalyzed by cytochrome P450 3A4.

Pub. Date : 1998 Aug

PMID : 9698298






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The BN N-dealkylation activities in 10 human liver microsomal preparations were strongly correlated with microsomal CYP3A-specific metabolic reactions, i.e. triazolam 1"-hydroxylation (r = 0.954), midazolam 1"-hydroxylation (r = 0.928), and testosterone 6beta-hydroxylation (r = 0.897). testosterone 6beta cytochrome P450 family 3 subfamily A member 4 Homo sapiens