Pub. Date : 1998 Aug
PMID : 9688614
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Administration of DFMO not only depleted intracellular polyamines but also significantly increased the mRNA levels of TGF-beta. | Eflornithine | transforming growth factor, beta 1 | Rattus norvegicus |
| 2 | Increased TGF-beta mRNA in DFMO-treated cells was paralleled by an increase in TGF-beta content. | Eflornithine | transforming growth factor, beta 1 | Rattus norvegicus |
| 3 | Increased TGF-beta mRNA in DFMO-treated cells was paralleled by an increase in TGF-beta content. | Eflornithine | transforming growth factor, beta 1 | Rattus norvegicus |
| 4 | The half-life of mRNA for TGF-beta in normal cells was approximately 65 min and increased to >16 h in cells treated with DFMO for 6 or 12 days. | Eflornithine | transforming growth factor, beta 1 | Rattus norvegicus |
| 5 | Exogenous polyamine, when given together with DFMO, prevented the increased half-life of TGF-beta mRNA in IEC-6 cells. | Eflornithine | transforming growth factor, beta 1 | Rattus norvegicus |