Title : Investigation of hepatic cytochrome P-450 enzyme induction and DNA adduct formation in male CD/1 mice following oral administration of toxaphene.

Pub. Date : 1998 May-Jun

PMID : 9685045






2 Functional Relationships(s)
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1 Significant increases in immunodetectable levels of CYP 2B were, however, detected in toxaphene-treated mice, and are consistent with earlier reports demonstrating that toxaphene, like many other pesticides, induces the phenobarbital-inducible subfamily of CYP. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus
2 Significant increases in immunodetectable levels of CYP 2B were, however, detected in toxaphene-treated mice, and are consistent with earlier reports demonstrating that toxaphene, like many other pesticides, induces the phenobarbital-inducible subfamily of CYP. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus