Pub. Date : 1998 Aug 1
PMID : 9683525
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of the cell cycle at the G2/M boundary in metastatic melanoma cells by 12-O-tetradecanoyl phorbol-13-acetate (TPA) by blocking p34cdc2 kinase activity. | Tetradecanoylphorbol Acetate | cyclin dependent kinase 1 | Homo sapiens |
| 2 | Regulation of the cell cycle at the G2/M boundary in metastatic melanoma cells by 12-O-tetradecanoyl phorbol-13-acetate (TPA) by blocking p34cdc2 kinase activity. | Tetradecanoylphorbol Acetate | cyclin dependent kinase 1 | Homo sapiens |
| 3 | Examination of the levels of cyclins A and B1 demonstrated that the levels of these cyclins were not limiting for entrance into M. However, the addition of TPA blocked the increase in p34(cdc2)/cyclin B1 kinase activity. | Tetradecanoylphorbol Acetate | cyclin dependent kinase 1 | Homo sapiens |
| 4 | In cells treated with TPA, most p34(cdc2) was found in the slowly migrating forms on Western blots, which contained increased levels of phosphotyrosine. | Tetradecanoylphorbol Acetate | cyclin dependent kinase 1 | Homo sapiens |