Title : Mutant p53 protein expression interferes with p53-independent apoptotic pathways.

Pub. Date : 1998 Jun 25

PMID : 9681825






1 Functional Relationships(s)
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1 Apoptosis caused by DNA damage induced with gamma-irradiation, doxorubicin or cisplatin, was enhanced in cells expressing wild type p53 as compared to that seen in parental p53 non-producer cells; mutant p53 expressing clones were found to be more resistant to apoptosis induced by these factors. Cisplatin tumor protein p53 Homo sapiens