Pub. Date : 1998 Jul
PMID : 9681711
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The blunting of the antiproteinuric efficacy of ACE inhibition by high sodium intake can be restored by hydrochlorothiazide. | Sodium | angiotensin I converting enzyme | Homo sapiens |
| 2 | BACKGROUND: Dietary sodium restriction enhances the antiproteinuric and blood pressure lowering effect of ACE inhibition. | Sodium | angiotensin I converting enzyme | Homo sapiens |
| 3 | We therefore investigated whether the blunting of the antiproteinuric and blood pressure lowering efficacy of ACE inhibition by high sodium intake can be restored by the addition of a diuretic. | Sodium | angiotensin I converting enzyme | Homo sapiens |
| 4 | CONCLUSION: Addition of hydrochlorothiazide can overcome the blunting of the therapeutic efficacy of ACE inhibition on proteinuria and blood pressure by a high sodium intake. | Sodium | angiotensin I converting enzyme | Homo sapiens |