Title : Lectin-dependent modulation of interaction between human alpha-fetoprotein and its monoclonal antibodies. Epitope mapping.

Pub. Date : 1998

PMID : 9679744






1 Functional Relationships(s)
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1 The enhanced binding of some MoAbs to AFP-L3 over AFP-L1 with LCA, or both glycoforms of AFP with concanavalin A, may be explained by postulating an allosteric mechanism mediated by the oligosaccharide-lectin interaction. Oligosaccharides alpha fetoprotein Homo sapiens