Pub. Date : 1998 Jul 31
PMID : 9677415
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein. | Lysine | tumor protein p53 | Homo sapiens |
| 2 | Mutagenesis analysis demonstrated that a single amino acid mutation of Lys-305 (mt p53) caused cytoplasmic sequestration of the p53 protein in the MCF-7 and RKO cells, whereas the fusion protein was distributed in both the cytoplasm and the nucleus of SAOS-2 cells. | Lysine | tumor protein p53 | Homo sapiens |
| 3 | Mutagenesis analysis demonstrated that a single amino acid mutation of Lys-305 (mt p53) caused cytoplasmic sequestration of the p53 protein in the MCF-7 and RKO cells, whereas the fusion protein was distributed in both the cytoplasm and the nucleus of SAOS-2 cells. | Lysine | tumor protein p53 | Homo sapiens |
| 4 | Lys-305 is needed for nuclear import of p53 protein, and amino acid residues 326-355 can sequester mt p53 in the cytoplasm. | Lysine | tumor protein p53 | Homo sapiens |
| 5 | Lys-305 is needed for nuclear import of p53 protein, and amino acid residues 326-355 can sequester mt p53 in the cytoplasm. | Lysine | tumor protein p53 | Homo sapiens |