Pub. Date : 1998 May-Jun
PMID : 9673414
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of wild-type p53 in the enhancement of camptothecin cytotoxicity against human prostate tumor cells. | Camptothecin | tumor protein p53 | Homo sapiens |
| 2 | The role of wild-type human p53 protein in enhancing camptothecin cytotoxicity was examined by infecting human prostate PC3 cells with adenovirus expressing human wild-type p53 gene (Adwtp53). | Camptothecin | tumor protein p53 | Homo sapiens |
| 3 | In the presence of camptothecin, an inhibitor of topoisomerase 1, significant increases in both p53 and p21 proteins were detected in Adwtp53-infected PC3 cells. | Camptothecin | tumor protein p53 | Homo sapiens |