Title : Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones.

Pub. Date : 1998 Jul 1

PMID : 9670864






1 Functional Relationships(s)
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1 In the present study, we have examined the expression of DP IV/CD26 on six myelin basic protein (MBP)(87-99)-specific, CD4+ T cell clones (TCC) derived from patients with multiple sclerosis (MS) as well as the biological effects of the two synthetic DP IV inhibitors Lys[Z(NO2)]-thiazolidide and Lys[Z(NO2)]-pyrrolidide on the function of these cells. lysyl-(Z(nitro))thiazolidide dipeptidyl peptidase 4 Homo sapiens