Title : IL-10 down-regulates human microglial IL-8 by inhibition of NF-kappaB activation.

Pub. Date : 1998 Jun 1

PMID : 9665590






2 Functional Relationships(s)
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1 NF-kappaB involvement was suggested by the finding that pyrrolidinedithiocarbamate, a known inhibitor of NF-kappaB activation, blocked LPS- and IL-1beta-induced IL-8 production. pyrrolidine dithiocarbamic acid nuclear factor kappa B subunit 1 Homo sapiens
2 NF-kappaB involvement was suggested by the finding that pyrrolidinedithiocarbamate, a known inhibitor of NF-kappaB activation, blocked LPS- and IL-1beta-induced IL-8 production. pyrrolidine dithiocarbamic acid nuclear factor kappa B subunit 1 Homo sapiens