Title : Autocrine regulation of matrix metalloproteinase-9 gene expression and secretion by tumor necrosis factor-alpha (TNF-alpha) in NB4 leukemic cells: specific involvement of TNF receptor type 1.

Pub. Date : 1998 Jul

PMID : 9665201






2 Functional Relationships(s)
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1 Whereas 12-O-tetradecanoylphorbol-13 acetate (TPA) increased both MMP-9 and TIMP-1 mRNA levels, tumor necrosis factor-alpha (TNF-alpha) stimulated only MMP-9 gene expression in a dose- and time-dependent manner. Tetradecanoylphorbol Acetate TIMP metallopeptidase inhibitor 1 Homo sapiens
2 Whereas 12-O-tetradecanoylphorbol-13 acetate (TPA) increased both MMP-9 and TIMP-1 mRNA levels, tumor necrosis factor-alpha (TNF-alpha) stimulated only MMP-9 gene expression in a dose- and time-dependent manner. Tetradecanoylphorbol Acetate TIMP metallopeptidase inhibitor 1 Homo sapiens