Pub. Date : 1998 Jun 11
PMID : 9662335
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lysophosphatidic acid-induced association of SHP-2 with SHPS-1: roles of RHO, FAK, and a SRC family kinase. | lysophosphatidic acid | PTK2 protein tyrosine kinase 2 | Mus musculus |
| 2 | LPA-induced tyrosine phosphorylation of SHPS-1 was markedly reduced in either focal adhesion kinase (FAK)-deficient mouse cells or CHO cells overexpressing the tyrosine kinase CSK. | lysophosphatidic acid | PTK2 protein tyrosine kinase 2 | Mus musculus |
| 3 | LPA-induced tyrosine phosphorylation of SHPS-1 was markedly reduced in either focal adhesion kinase (FAK)-deficient mouse cells or CHO cells overexpressing the tyrosine kinase CSK. | lysophosphatidic acid | PTK2 protein tyrosine kinase 2 | Mus musculus |
| 4 | These results indicate that LPA-induced tyrosine phosphorylation of SHPS-1 and its association with SHP-2 may be mediated by a RHO-dependent pathway that includes FAK and a SRC family kinase. | lysophosphatidic acid | PTK2 protein tyrosine kinase 2 | Mus musculus |