Title : Thymidine phosphorylase moderates thymidine-dependent rescue after exposure to the thymidylate synthase inhibitor ZD1694 (Tomudex) in vitro.

Pub. Date : 1998 Jul 1

PMID : 9661884






2 Functional Relationships(s)
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1 Thymidine phosphorylase moderates thymidine-dependent rescue after exposure to the thymidylate synthase inhibitor ZD1694 (Tomudex) in vitro. Thymidine thymidylate synthetase Homo sapiens
2 The inhibition of de novo thymidine (dThd) synthesis by the novel folate-based thymidylate synthase (TS) inhibitor ZD1694 (Tomudex) can achieve tumor cell-specific cytotoxicity in vivo. Thymidine thymidylate synthetase Homo sapiens