Title : The role of histamine in platelet aggregation by physiological and immunological stimuli.

Pub. Date : 1998 May

PMID : 9657253






2 Functional Relationships(s)
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1 The exposure of platelets to thrombin (10-60 mUml(-1)) produced a progressive aggregation, associated with histamine release. Histamine coagulation factor II, thrombin Homo sapiens
2 In resting platelets cytosolic calcium level (207 +/- 4.2 nM/10(8) platelets) is increased by thrombin as well as by anti-IgE; this effect is potentiated by 10(-5) M histamine. Histamine coagulation factor II, thrombin Homo sapiens