Title : Cytokine production by CD4+ and CD8+ T cells in mice following primary exposure to chemical allergens: evidence for functional differentiation of T lymphocytes in vivo.

Pub. Date : 1998 Jun

PMID : 9652304






5 Functional Relationships(s)
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1 Chronic exposure of mice to contact allergens, such as 2,4-dinitrochlorobenzene (DNCB), resulted in the secretion by LNC of low or undetectable levels of interleukins 4 and 10 (IL-4 and IL-10), but comparatively high levels of interferon gamma (IFN-gamma); the latter cytokine being produced by both CD4+ and CD8+ cells. Dinitrochlorobenzene interleukin 4 Mus musculus
2 Chronic exposure of mice to contact allergens, such as 2,4-dinitrochlorobenzene (DNCB), resulted in the secretion by LNC of low or undetectable levels of interleukins 4 and 10 (IL-4 and IL-10), but comparatively high levels of interferon gamma (IFN-gamma); the latter cytokine being produced by both CD4+ and CD8+ cells. Dinitrochlorobenzene interleukin 4 Mus musculus
3 Chronic exposure of mice to contact allergens, such as 2,4-dinitrochlorobenzene (DNCB), resulted in the secretion by LNC of low or undetectable levels of interleukins 4 and 10 (IL-4 and IL-10), but comparatively high levels of interferon gamma (IFN-gamma); the latter cytokine being produced by both CD4+ and CD8+ cells. Dinitrochlorobenzene interleukin 4 Mus musculus
4 Chronic exposure of mice to contact allergens, such as 2,4-dinitrochlorobenzene (DNCB), resulted in the secretion by LNC of low or undetectable levels of interleukins 4 and 10 (IL-4 and IL-10), but comparatively high levels of interferon gamma (IFN-gamma); the latter cytokine being produced by both CD4+ and CD8+ cells. Dinitrochlorobenzene interleukin 4 Mus musculus
5 It was found that primary exposure to DNCB, oxazolone and TMA each resulted in the production by LNC of both IFN-gamma and IL-4. Dinitrochlorobenzene interleukin 4 Mus musculus